About this item
Doctors Best Best Acetyl-L-Carnitine (ALC) is a naturally occurring form of L-Carnitine, a vitamin-like nutrient synthesized in the body from the amino acids lysine and methionine. ALC plays a key role in the production of acetylcholine, an important neurotransmitter for brain and nerve cell function. The Acetyl-L-Carnitine in this product is derived from a base of pharmaceutical grade L-Carnitine manufactured by patented, FDA-approved process that fully complies with the USP 25, FCC 4 and EU monographs. It is GMO-free, pesticide-free and BSE safe. Features & Benefits: Science-Based Nutrition Dietary supplement Beneficial antioxidant protection Enhances alertness and mental focus Supports energy metabolism in the brain Keeps nerves healthy and in repair Decreases free radical production in the brain Supports Cognitive Function ALC has been studied for its effect on cognitive performance and emotional health in the elderly. Supports Biosynthesis of Acetylcholine, a Key Neurotransmitter for Brain and Nerve Function. Brain function requires coordinated communication between brain cells. Neurons (brain & nerve cells) communicate across tiny cell-to-cell gaps called synapses. The passage of an electrical impulse from one neuron to the next requires a neurotransmitter to act as a messenger to pass signals to adjacent neurons. When an electrical signal arrives at the synaptic junction, the neuron releases a neurotransmitter into the synapse. The neuron on the other side of the synapse contains receptors for the neurotransmitter (that will bind it), triggering a series of chemical events to send a new electrical signal down the membrane of the receiving neuron. Neurotransmitters work together like an orchestra to transmit information throughout the brain and nervous system. Acetylcholine is the most abundant neurotransmitter in the body, regulating activities of vital organs and blood vessels, and communication between nerves and muscles. In the brain, acetylcholine helps to facilitate memory and learning, as well as influencing emotions. ALC is structurally similar to acetylcholine? enough so that brain neurons stimulated by acetylcholine are receptive to stimulation by ALC. Helps Supply the Brain With Energy Through Mitochondrial Efficiency. The acetyl groups donated by ALC can be used to naturally synthesize acetyl-CoA, the key substrate for energy metabolism in the mitochondrion. Acetyl-CoA enters the Krebs cycle, the mitochondrial pathway that generates cellular energy in the form of ATP. The effects of decreased mitochondrial oxidative capacity are especially prevalent in organs that require high-energy inputs, such as the brain and heart. Recent clinical studies have shown that ALC helps to promote and maintain healthy mitochondrial function. Helps Uphold the Integrity of Intracellular Membranes Phospholipids are structural components of brain cell membranes that regulate neuronal function. ALC promotes normal membrane function, stability, and structural integrity. Supports Nerve Growth Factor Production. The body produces specialized proteins called growth factors that are essential to the growth and repair of tissue. Nerve Growth Factor (NGF) prolongs the survival of neurons in both the central and peripheral nervous systems. Supports Healthy Brain Neuron Function. ALC also reduces blood levels of MDA (malondialdehyde), a free radical byproduct. Furthermore, ALC is a chelator of iron: it acts as a molecule that can naturally sequester iron in the body to prevent iron-mediated oxidative damage to cells. As a whole, data from in vitro and animal studies suggest that ALC is effective towards the maintenance of healthy brain neurons and normal neuronal energetic processes. This hypothesis is supported by human studies that demonstrate the potential of ALC to promote healthy brain function in elderly persons.
Acetyl-L-Carnitine (from 588mg acetyl-l-carnitine HCl supplied by Sigma tau), stearic acid, cellulose, magnesium silicate, silicon dioxide, gelatin capsule.
As a dietary supplement, take 1 to 4 capsules daily with or without food.